Saturday, March 8, 2008

Human Body Chemical Composition

Thursday, March 27, 2008 at 7:03:55 PM EDT
*This article will be edited as new information is found.



The human body consists of ~7 x 1027 atoms arranged in a highly aperiodic physical structure. Although 41 chemical elements are commonly found in the body's construction, CHON comprises 99% of its atoms. Fully 87% of human body atoms are either hydrogen or oxygen.

 

Estimated Atomic Composition
of the Lean 70-kg Male Human Body

Element

Sym

# of Atoms

Hydrogen

H

4.22 x 1027

Oxygen

O

1.61 x 1027

Carbon

C

8.03 x 1026

Nitrogen

N

3.9 x 1025

Calcium

Ca

1.6 x 1025

Phosphorus

P

9.6 x 1024

Sulfur

S

2.6 x 1024

Sodium

Na

2.5 x 1024

Potassium

K

2.2 x 1024

Chlorine

Cl

1.6 x 1024

Magnesium

Mg

4.7 x 1023

Silicon

Mg

3.9 x 1023

Fluorine

F

8.3 x 1022

Iron

Fe

4.5 x 1022

Zinc

Zn

2.1 x 1022

Rubidium

Rb

2.2 x 1021

Strontium

Sr

2.2 x 1021

Bromine

Br

2 x 1021

Aluminum

Al

1 x 1021

Copper

Cu

7 x 1020

Lead

Pb

3 x 1020

Cadmium

Cd

3 x 1020

Boron

B

2 x 1020

Manganese

Mn

1 x 1020

Nickel

Ni

1 x 1020

Lithium

Li

1 x 1020

Barium

Ba

8 x 1019

Iodine

I

5 x 1019

Tin

Sn

4 x 1019

Gold

Au

2 x 1019

Zirconium

Zr

2 x 1019

Cobalt

Co

2 x 1019

Cesium

Cs

7 x 1018

Mercury

Hg

6 x 1018

Arsenic

As

6 x 1018

Chromium

Cr

6 x 1018

Molybdenum

Mo

3 x 1018

Selenium

Se

3 x 1018

Beryllium

Be

3 x 1018

Vanadium

V

8 x 1017

Uranium

U

2 x 1017

Radium

Ra

8 x 1010

 

 

 

 

 

 

TOTAL

 

6.71 x 1027

 

Somatic atoms are generally present in combined form as molecules or ions, not individual atoms. The molecules of greatest nanomedical interest are incorporated into cells or circulate freely in blood plasma or the interstitial fluid. Table 3-2 summarizes the gross molecular contents of the typical human cell, which is 99.5% water and salts, by molecule count, and contains ~5000 different types of molecules. Appendix B lists 261 of the most common molecular and cellular constituents of human blood, and their normal concentrations in whole blood and plasma. This listing is far from complete. The human body is comprised of ~105 different molecular species, mostly proteinsemdasha large but nonetheless finite molecular parts list. By 1997, at least ~104 of these proteins had been sequenced, ~103 had been spatially mapped, and ~7,000 structures (including proteins, peptides, viruses, protein/nucleic acid complexes, nucleic acids, and carbohydrates) had been registered in the Protein Data Bank maintained at Brookhaven National Laboratory.

 

Estimated Gross Molecular Contents
of a Typical 20-micron Human Cell

Molecule

Mass %

MW (daltons)

# Molecules

Molecule %

Number of
Molecular Types

Water

65%

18

1.74 x 1014

98.73 %

1

Other Inorganic

1.5%

55

1.31 x 1012

0.74 %

20

Lipid

12%

700

8.4 x 1011

0.475 %

50

Other Organic

0.4%

250

7.7 x 1010

0.044 %

~200

Protein

20%

50,000

1.9 x 1010

0.011 %

~5,000

RNA

1.0%

1 x 106

5 x 107

3 x 10-5 %

----

DNA

0.1%

1 x 1011

46

3 x 10-11 %

----

 

 

 

 

 

 

TOTALS

100%

----

1.76 x 1014

100%

----

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